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21.
ABSTRACT

The length of telomeres is an objective measure of biologic ageing. This study evaluated the extent minutes of walking per week are associated with leukocyte telomere length (LTL) in a random sample of 5,823 U.S. adults. The investigation was cross-sectional and data were obtained from the National Health and Nutrition Examination Survey (NHANES). LTL was measured by the quantitative polymerase chain reaction method. Walking minutes was calculated from walking frequency and duration measures. Results showed that for each year of chronological age, telomeres were 15.6 base pairs shorter (P < 0.0001). With walking minutes and LTL treated as continuous variables, the relationship was quadratic, not linear (F = 11.2, P = 0.0023). With walking time divided into three categories, adults who performed ≥ 150 minutes of walking per week had longer telomeres than those who did no regular walking, and those who did some, but less than the recommendation (F = 5.0, P = 0.0137). Regular walkers were estimated to have a biologic ageing advantage associated with 6.5–7.6 years less biologic ageing compared to non-walkers, after adjusting for covariates. Additional investigations designed to study causality and the mechanisms associated with the walking and LTL relationship are needed.  相似文献   
22.
ABSTRACT

The purpose of this study was to explore the respiratory response of acute interval and continuous exercise (CE) of low and high intensity. Fourteen recreational athletes (7 men and 7 women; VO2max = 35.7 ± 6.1 mlkg–1min–1) performed a bout of continuous and a bout of interval exercise (IE) both consisted of 5-min cycling at low intensity [80% of the power output (W) of the predetermined gas exchange threshold (GET) (80%WGET)] and 5-min cycling at high intensity {WGET plus the work rate corresponding to 50% of the difference between peak power output (PPO) at oxygen uptake (VO2max) test and the WGET [WGET + 0.50 Δ(PPO – WGET)]}. CE compared to IE induced significant higher heart rate and ventilation as well as significant higher levels of mouth occlusion pressure for 0.1 s (P0.1) (P < 0.05) during low and high intensities. Our results indicate that CE stimulates respiration more than IE when the exercise is performed at the same relative intensity.  相似文献   
23.
由于新型冠状病毒(2019-nCoV)感染的肺炎疫情暴发,人们将居家运动作为提高免疫力与保持健康的重要手段,运动与免疫的关系再度受到关注。一般认为,在充分恢复的前提下进行规律的中高强度运动可提高免疫功能,而急性运动(acute exercise)可能抑制免疫功能并增加感染风险。急性运动后外周血淋巴细胞计数及功能降低、免疫球蛋白A水平分泌减少被认为是运动抑制免疫的理论基础。但目前这种独立于非运动因素影响免疫功能增加感染风险的认识受到了现有研究的挑战。急性运动可通过应激反应将淋巴细胞亚群迅速动员至循环中,运动结束后,淋巴细胞亚群又会迅速迁移至外周组织。淋巴细胞的重新分布(lymphocyte redeployment)可能是一种进化保守的免疫机制,这一过程强化了外周组织的免疫监视与调节功能,有助于提升机体抵抗感染能力。因此,从这一视角就急性运动对机会性感染风险及免疫功能影响的现状进行综述。  相似文献   
24.
目的考察适应性完美主义、自主动机对青少年锻炼坚持性的综合影响,检验父母自主支持的调节效应。方法修订父母社会背景调查问卷(家长报告)的自主支持分量表、中文Frost多维度完美主义问卷的个人标准和条理性分量表、因果控制点知觉量表和青少年户外运动坚持性量表,对2230名12~18岁青少年及其家长进行调查,分析适应性完美主义对青少年锻炼坚持性的间接影响。结果父母自主支持、青少年的适应性完美主义和自主动机对锻炼坚持性正向影响皆显著,分别解释了3.7%、30.3%和38.3%的变异;在适应性完美主义与青少年锻炼坚持性的影响链条上,自主动机的中介效应、父母自主支持的中介调节效应、性别的调节中介效应皆显著,三者共同的间接效应值为0.426,占总效应的77.45%。结论适应性完美主义既能直接影响青少年的锻炼坚持性,又能通过自主动机的中介而间接作用于锻炼坚持性;父母对青少年体育锻炼的自主支持能够对青少年的适应性完美主义和锻炼自主动机产生积极的调节作用;相较于女性青少年,男性青少年的锻炼自主动机更强烈、锻炼亦更具坚持性。  相似文献   
25.
本文采用文献资料法、综述法,以"运动处方""治疗""抑郁症"等为关键词,在中国知网、超星发现等文献网站,搜索相关文献,进行归纳总结。得出结论并提出建议,旨在整理出运动处方治疗抑郁症的研究现状,为今后的研究发展提供参考。  相似文献   
26.
The notion that the stories of our lives shape dispositions towards imagined futures is another lens through which university underrepresentation should be viewed. A storied lens attends to how futures, like university attendance, are storied during childhood to the extent that some youth imagine, and therefore plan, these futures as natural progression. Such was the case for study participants, indicating that childhood stories contain answers for mitigating social reproduction connected to parental education and cultural forces within the home. Examining social mobility through the underexplored storied-futures grand narrative presents unique solutions that lay hidden within the dominant meritocratic grand narrative.  相似文献   
27.
This article examines the printed representation, and prosecutorial characterisation, of the movements, actions and motivations of early Quakers as vagrant. It argues that the prevalence and power of representing (and subsequently treating) early Quakers as vagrants is an understudied aspect of the social and cultural history of the Society of Friends, particularly in Interregnum England. As evidence, it interrogates a furious pamphlet debate between mid-century religious writers and preachers, who devoted much time and ink to painting Quakers as mendacious vagabonds, and Quaker ‘First Publishers’, who responded at length and in a striking way to these accusations. The article concludes that these images of Quakerism as a form of ‘spiritual vagrancy’ created historically significant echoes in English and Atlantic culture.  相似文献   
28.
This paper explores the affordances of using video-based research to capture a multiplicity of events, along with multimodal representations when producing data related to adult–child book readings. In doing this we answer two questions: (1) why more than one event is needed when seeking a comprehensive collection of information for the purpose of analysis; and (2) why one mode of data production alone (e.g. audio recordings or note taking) is insufficient to record practice or interviews when richness is of priority. This research used three videoed events to produce data. These included videoing: (1) caregiver–child interactions during four shared book reading sessions, (2) interviews with caregivers immediately following each of the reading sessions and (3) video-stimulated discussions with caregivers within two months of the final shared book reading. In this paper, I contribute to discussions that highlight the affordances of using video-based research as a means of capturing the multimodal elements of an experience, which can contribute to the analysis and interpretation of data. I expand on this, however, to suggest that when coupled with a multiplicity of events, video-based research can be a means of pursuing richness via a method that has been criticized for its narrow subjectivity.  相似文献   
29.
ABSTRACT

The systematic review and meta-analysis evaluated the effect of aerobic, resistance and combined exercise on RMR (kCal·day-1) and performed a methodological assessment of indirect calorimetry protocols within the included studies. Subgroup analyses included energy/diet restriction and body composition changes. Randomized control trials (RCTs), quasi – RCTs and cohort trials featuring a physical activity intervention of any form and duration excluding single exercise bouts were included. Participant exclusions included medical conditions impacting upon RMR, the elderly (≥65 years of age) or pregnant, lactating or post-menopausal women. The review was registered in the International Prospective Register of Systematic Reviews (CRD 42,017,058,503). 1669 articles were identified; 22 were included in the qualitative analysis and 18 were meta-analysed. Exercise interventions (aerobic and resistance exercise combined) did not increase resting metabolic rate (mean difference (MD): 74.6 kCal·day-1[95% CI: ?13.01, 161.33], P = 0.10). While there was no effect of aerobic exercise on RMR (MD: 81.65 kCal·day-1[95% CI: ?57.81, 221.10], P = 0.25), resistance exercise increased RMR compared to controls (MD: 96.17 kCal·day-1[95% CI: 45.17, 147.16], P = 0.0002). This systematic review effectively synthesises the effect of exercise interventions on RMR in comparison to controls; despite heterogenous methodologies and high risk of bias within included studies.  相似文献   
30.
ABSTRACT

Interval exercise training is increasingly recommended to improve health and fitness; however, it is not known if cardiovascular risk is different from continuous exercise protocols. This systematic review with meta-analyses assessed the effect of a single bout of interval exercise on cardiovascular responses that indicate risk of cardiac fibrillation and infarction compared to continuous exercise. Electronic databases Medline, CINAHL, Embase, Scopus and Cochrane were searched. Key inclusion criteria were: (1) intervals of the same intensity and duration followed by a recovery period and (2) reporting at least one of blood pressure, heart rate variability, arterial stiffness or function. Cochrane Risk of Bias tool and GRADE approach were used. Meta-analyses found that systolic blood pressure responses to interval exercise did not differ from responses to continuous exercise immediately (MD 8 mmHg [95% CI ?32, 47], p = 0.71) or at 60 min following exercise (MD 0 mmHg [95% CI ?2, 1], p = 0.79). However, reductions in diastolic blood pressure and flow-mediated dilation with interval exercise were observed 10–15 min post-exercise. The available evidence indicates that interval exercise does not convey higher cardiovascular risk than continuous exercise. Further investigation is required to establish the safety of interval exercise for clinical populations.  相似文献   
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